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1. Gene mutations are alterations in the DNA code.

2. Gene mutations occur spontaneously and can be induced by mutagenic agents such has high temperature, mustard gas, and radiation.

3. Other workers have found ras gene mutations in between 39% and 47% of colorectal cancers.

4. K-ras gene mutations, by contrast with p53, clearly occur at an earlier stage in the neoplastic sequence.

5. Conclusion Abore point mutation is an inherited gene mutation.

6. AIM:To investigate gene mutation of patient with oligodontia.

7. Conclusion PTEN gene mutation might play important role in tumor genesis and development of bladder cancer.

8. Objective : To analyze G 6 PD gene mutation in 168 Cantonese G 6 PD deficient male infants.

9. Variations of flower color are related to gene mutation and pollination pattern and so on.

10. Conclusion: E2 of NF2 gene mutation might be one of the critical factor in the tumorogenesis of acoustic neuromas .

11. Objective To establish TK gene mutation assay using human lymphoblastoid cell line TK6 and to study the genotoxic mechanism of Vinblastine(VBL).

12. Objective: To exclude known gene mutation, 21 exon of SOS1 which had been certified by foreign country form 2 families with hereditary gingival fibromatosis .

13. Objective To study the gene mutation and clinical characteristics of hereditary spinocerebellar ataxia type 7 (SCA7).

14. The variegation of petals originates chiefly from gene mutation and viral infection.

15. Ras gene mutation in childhood AML was mainly found in M 2 , M 4 , M 5 subtypes.

16. HBV gene mutation along different types of TCM syndrome are detected by microarray assay.

17. Objective To study the gene mutation in a pedigree with Dowling - Meara type epidermolysis bullosa simplex ( DM - EBS ).

18. Conclusion There is K 14 1 A domain gene mutation in this DM - EBS pedigree.

19. Objective To explore SCA3 gene mutation in the patients with inherited spinocerebellar ataxia.

20. Conclusion Maybe there is no association with E237G gene mutation between asthma and atopy.

21. Enough premalignant cells are present in the bulk of stool to permit the analysis of tumour suppressor gene mutations by this technique.

22. In order to explore the effect of precedent mutation on the sensitivity to mutagens the mutants resistant to 6 thioguanine (6 TG) were selected by 6 TG using gene mutation assay in V79 cells.

23. Absreact: This experiment was conducted to study the influence of growth hormone receptor(GHR) gene mutation on the semen quality of sex-linked dwarf chicken.

24. Single strand conformation polymorphism (SSCP) essay and sequence analysis of the PCR product were used to ascertain the gene mutation.

25. Conclusion The assumable reasons for the dominance of heterozygous ADH2 genotype were a relatively small size of samples or gene mutation etc, which needed further researches to be confirmed.

26. Each of them has its advantages. Selecting appropriate method would provide much better approaches for gene mutation analysis.

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27. Conclusbo : It'suggsts that ras gene aed p 53 gene mutation may be related with L - form infedtbo.

28. Objective:To assess the roles of single stranded conformation polymorphism(SSCP)and heteroduplex polymorphism(HET)in screening gene mutation.

29. Hypoxanthine guanine Phosphoribosyl Transferase(HPRT) is a classical gene locus in the research of single gene mutation.

30. Objective To detect the activity of transglutaminase 1 ( TGM 1 ) and gene mutation in a family with lamellar ichthyosis.